Growth Hormone Deficiency – Childhood

Medical information to support a TUE application – Growth Hormone Deficiency (Childhood)

Growth Hormone deficiency refers to a disorder of the hypothalamus or pituitary gland in which Growth Hormone production is impaired. Treatment of Growth Hormone deficiency is by supplementation with Growth Hormone, which is prohibited at all times in sport.

 

What information is required for a Therapeutic Use Exemption (TUE) application?

ASDMAC will not consider granting a TUE without the following information:

  • A completed TUE application form signed by the treating doctor and athlete.
  • Detailed typed clinical letter(s) from treating endocrinologist/paediatrician that includes:
    • accurate diagnosis – full clinical history and thorough examination including:
      • assessment of presence of chronic disease or genetic disorders
      • measurement of height with comparison to gender and ethnic norms
      • calculation of height velocity, and
      • radiological evaluation of bone age and MRI of hypothalamus.
    • age of onset of symptoms and of diagnosis
    • provision of relevant blood test and other relevant imaging results confirming the diagnosis
    • current treatment must be outlined, including name of medication/s, route of administration, dose and frequency, and
    • reports of monitoring of response to treatment.

NOTE: A clinical letter can be a copy of a specialist’s letter to another doctor (e.g. a GP), and at least one of the clinical letters submitted with the application must have been written in the last 12 months.

  • Supplementary reports (if available) that support the diagnosis, including:
    • blood test results growth factor concentrations:
      • insulin-like growth factor-1 (IGF-1)
      • insulin-like growth factor binding protein (IGFBP-3)
      • growth hormone stimulation tests
    • relevant imaging reports.

 

For additional information please refer to the medical information relating to the condition on the WADA website.